Steven D. Quinn

The paper investigates how the 2A protein interacts with the RNA genome of cardioviruses to activate ribosomal frameshifting through structural changes in the RNA.

This paper introduces a fluorescence de-quenching assay to study detergent-induced membrane remodeling, showing Triton X-100 causes morphological transitions at sub-critical concentrations.

This study investigates the conformational transitions of Rep helicase using single-molecule techniques, revealing two intermediate states influenced by salt concentration.

This paper develops a DNA scaffold method for 5' labeling of SARS-CoV-2 RNA pseudoknots to study their conformational dynamics using smFRET.

This paper demonstrates pH-responsive DNA nanoswitches immobilized on surfaces, showing reversible and repeatable switching, and introduces electrically driven actuation for potential hybrid electronic-DNA technologies.

This study identifies multiple intermediates in detergent-induced vesicle fusion using FRET and single-vesicle analysis, revealing a multi-step mechanism involving permeabilization, docking, hemi-fusion, and lipid mixing.

This study develops a molecular model to investigate how hydrophobicity drives amyloid beta aggregation, showing that A{beta}1-42 enrichment in plaques is due to hydrophobic interactions promoting phase separation.