Molecular BiologyBiomaterialsPeer-reviewed
Engineered extracellular vesicle decoy receptor-mediated modulation of the IL6 trans-signalling pathway in muscle
Mariana Conceição, Laura Forcina, Oscar P. B. Wiklander…·Thomas C. Roberts
This study engineers extracellular vesicles with IL6ST decoy receptors to inhibit the IL6 trans-signalling pathway, showing efficacy in vitro and in a Duchenne muscular dystrophy mouse model.
45 citations