Author

Yunsen Zhang

University of Illinois Urbana-ChampaignORCID 0000-0003-3476-6728Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:drug response / drug discovery· 2 Assay:multiome· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Assay:cryo-EM· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Andrei N. LupasiD· 1 shared Aurora PanzeraiD· 1 shared Birte Hernandez AlvareziD· 1 shared Defang OuyangiD· 1 shared Emad TajkhorshidiD· 1 shared Hang Yu· 1 shared Hao Shuang GuiD· 1 shared Hassane S. MchaourabiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperBiochemistry

Andrei N. LupasORCID

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3 papers

Recent·Most cited

BiochemistryNature CommunicationsPeer-reviewedDec 11, 2025

DNA Wrapping by a Tetrameric Bacterial Histone

Yimin Hu, Samuel Schwab, Kaiyu Qiu…·Birte Hernandez Alvarez

This study characterizes HLp, a bacterial histone that forms tetramers and wraps ~60 base pairs of DNA, revealing a new mode of histone-DNA interaction in bacteria.

7 citations

bacteria (other)DNA methylation

𝕏 PostBluesky

BiophysicsbioRxivPreprintFeb 26, 2025

Lipid-mediated mechanism of drug extrusion by a heterodimeric ABC exporter

Qingyu Tang, Matt Sinclair, Paola Bisignano…·Hassane S. Mchaourab

This study reveals how lipid competition modulates drug affinity in ABC exporters through structural and simulation analyses of BmrCD.

1 citation

cryo-EMmultiome

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BioengineeringbioRxivPreprintOct 13, 2023

Dual Ethanolamine Head Groups in Ionizable Lipids Facilitate Phospholipid-free Stable Nanoparticle Formulation for Augmented and Safer mRNA Delivery

Jing Lu, Ting Shun Jiang, Xuechun Li…·Jinzhong Lin

This paper introduces ionizable lipids with dual ethanolamine head groups for phospholipid-free mRNA delivery, showing improved stability, efficiency, and reduced toxicity.

7 citations

multiomeexperimental assay

𝕏 PostBluesky