Author

Hui Cai

Pfizer (United States)ORCID 0000-0003-3627-7346Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Adele XuiD· 1 shared Alexander MuikiD· 1 shared Alicia SolórzanoiD· 1 shared Andrew M. WatkinsiD· 1 shared Andrew P. McKeen· 1 shared Annaliesa S. AndersoniD· 1 shared Annette B. VogeliD· 1 shared Bojan Tunguz· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperMolecular Biology

Adele XuORCID

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2 papers

Recent·Most cited

Immunologynpj VaccinesPeer-reviewedNov 20, 2024

Preclinical Characterization of the Omicron XBB.1.5-Adapted BNT162b2 COVID-19 Vaccine

Kayvon Modjarrad, Ye Che, Wei Chen…·Kena A. Swanson

The monovalent Omicron XBB.1.5-adapted BNT162b2 mRNA vaccine elicits stronger neutralizing antibody responses against XBB.1.5 and related sublineages than the bivalent Wild Type + Omicron BA.4/5 vaccine.

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mouseexperimental assay

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Molecular BiologyNature CommunicationsPeer-reviewedMar 22, 2022

Combinatorial optimization of mRNA structure, stability, and translation for RNA-based therapeutics

Kathrin Leppek, Gun Woo Byeon, Wipapat Kladwang…·Rhiju Das

This study develops PERSIST-seq and In-line-seq to optimize mRNA stability and translation, finding that in-cell stability is more critical than ribosome load for protein output.

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humanmultiome

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