Chih‐Chia Su

This paper uses cryo-EM with the Build-and-Retrieve method to solve integrin αIIbβ3 structures from resting human platelet membranes, revealing new insights into its regulation and dimer conformation.

This paper identifies and improves efflux pump modulators (EPMs) that inhibit bacterial growth in macrophages and enhance antibiotic potency under host-like conditions.

This paper presents a cryo-EM structure of Drp1 dimer revealing conformational rearrangements that regulate its self-assembly and mitochondrial fission.