Author

Guha Asthagiri Arunkumar

Moderna Therapeutics (United States)ORCID 0000-0003-3665-2708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:multiome· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

Alec W. FreyniD· 1 shared Andrea Carfı́iD· 1 shared Anthony T. DiPiazzaiD· 1 shared Caroline G. AtyeoiD· 1 shared Cathal HarmoniD· 1 shared Chieh-Yu LiangiD· 1 shared Cory M. AcremaniD· 1 shared Daniel C. DouekiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

Alec W. FreynORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 5, 2025

A multivalent mRNA-LNP therapeutic vaccine with broad cross-genotype immunogenicity elicits clearance of HBV infected hepatocytes

Daniel L. Makrinos, Yanbo Sun, Heather L. Davis…·Simone Pecetta

This paper develops an mRNA-LNP vaccine, mRNA-1965, that clears HBV-infected hepatocytes in mice by inducing broad immune responses across HBV genotypes.

DOI 10.64898/2025.12.03.692117

mousenon-human primate

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ImmunologyNaturePeer-reviewedMay 15, 2024

Prototype mRNA vaccines imprint broadly neutralizing human serum antibodies after Omicron variant-matched boosting

Chieh-Yu Liang, Saravanan Raju, Zhuoming Liu…·Michael S. Diamond

This study shows that Omicron variant-matched boosters after prototype mRNA vaccines induce cross-neutralizing antibodies against SARS-CoV-2 and sarbecoviruses by imprinting prior immune responses.

94 citationstop 1%

humanmouse

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