Author
Universidade do PortoORCID 0000-0003-3679-4300Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Joana Saavedra, Mariana Nascimento, António J. Figueira…·Isabel Cardoso
This study shows that neuronal S100B expression is triggered by Aβ oligomers and protects against cytoskeletal damage and synaptic loss in Alzheimer's disease.
Tiago Gião, Miguel Tábuas‐Pereira, Inês Baldeiras…·Isabel Cardoso
This study examines TTR levels and instability in plasma and CSF across AD stages, finding associations with amyloid-beta, tau, and neuroinflammation markers.
Zsuzsa Sárkány, Tiago Gião, Márcia A. Liz…·Pedro Miguel Martins
This study shows that transthyretin (TTR) selectively proteolyzes specific conformations of alpha-synuclein (aSyn), preventing its aggregation, with implications for neurodegenerative diseases.
Tiago Gião, Joana Saavedra, José Ricardo Vieira…·Isabel Cardoso
This study shows that transthyretin (TTR) promotes angiogenesis and vascular health in Alzheimer's disease, with tetrameric stabilization offering a potential therapeutic strategy.