Pearl V. Ryder

The paper introduces NeuroPainting, a morphological phenotyping method, and combines it with transcriptomics to identify cell-type-specific effects of the 22q11.2 deletion on mitochondrial structure and gene expression in astrocytes.

This paper describes a postdoctoral training program in bioimage analysis, highlighting its components, outcomes, and implications for training experts in professional skills.

The paper develops a high-throughput imaging platform to assess the functional impact of missense variants on protein localization, finding that mislocalization is common in pathogenic variants.

This study identifies Sp7 and its target gene osteocrin as critical for osteocyte dendrite formation and shows their role in human skeletal diseases.

The paper investigates mRNA localization to centrosomes in Drosophila embryos, identifying FMRP's role in regulating centrosomal RNA and its impact on spindle formation and genome stability.