Udaykumar Ranga

This study identifies subtype-specific biochemical properties of HIV-1C reverse transcriptase that enhance sequence motif duplication through improved strand transfer and mismatch extension.

This paper develops a dual-reporter HTS assay to identify HIV-1 latency-modulating agents, finding 27 candidate LPAs and LRA compounds from a chemical library.

This study identifies HIV-1C LTR variants that influence latency and reservoir stability, showing R2 strains resist reversal and contribute to persistent reservoirs.

The paper compares cytokine-chemokine profiles induced by neurovirulent and non-neurovirulent HIV-1 strains and their Tat proteins, showing differential inflammatory responses.

This study optimizes the expression of HIV-1 Tat in Lactococcus lactis, showing functional transactivation of the HIV-1 promoter.