Frederik Ravnkilde Marlet

This study shows that terminal truncations of α-synuclein significantly alter phase separation, while familial mutations have minimal effects, influencing amyloid fibril formation and condensate behavior.

This study identifies shared and distinct lipid profile changes in amygdala from sporadic and GBA-associated Parkinson's Disease, linking lipid metabolism to alpha-synuclein and glucocerebrosidase activity.

This study characterizes lipidome changes during SH-SY5Y cell differentiation into dopaminergic neurons and links lipid levels to neuronal and dopaminergic markers.

The paper identifies Golgi fragmentation as an early AD phenotype in neurons using stem cell and mouse models, showing its link to SORL1 variants and glycosylation changes.