Kenji Maeda

This study identifies VPS13C/PARK23 as a key protein involved in lysosomal repair by facilitating lipid transfer and membrane remodeling in response to damage.

This study identifies shared and distinct lipid profile changes in amygdala from sporadic and GBA-associated Parkinson's Disease, linking lipid metabolism to alpha-synuclein and glucocerebrosidase activity.

This study shows that B cell-derived extracellular vesicles from activated B cells stimulate lytic gene expression of oncogenic herpesviruses.

The paper identifies lipid cargoes for half of analyzed human LTPs, revealing selectivity for lipid head groups and acyl chains and new lipid-organelle relationships.

The paper maps lipid species across human cell compartments using PAP-SL and identifies general rules of lipid organization and metabolic plasticity.

This study identifies TMEM165 as a lysosomal calcium importer that prevents calcium overload and regulates lysosomal pH.

This study uses molecular dynamics simulations to investigate how acidic sphingomyelinase interacts with lysosomal membranes and how cation amphiphilic drugs like ebastine affect these interactions.

LipidDyn is a computational pipeline that analyzes MD simulations of membranes with varying compositions to extract properties like area per lipid and thickness.