BiophysicsPNAS NexusPeer-reviewed
Dilated cardiomyopathy mutation in beta-cardiac myosin enhances actin activation of the power stroke and phosphate release
Skylar M.L. Bodt, Jinghua Ge, Wen Ma…·Christopher M. Yengo
This paper investigates how the E525K mutation in beta-cardiac myosin affects actin activation, power stroke, and phosphate release, revealing structural and kinetic changes linked to dilated cardiomyopathy.
12 citations