Rafael Romero-Becerra

This paper develops a domain-adversarial neural network to predict drug combination synergy in leukemia patients using bulk transcriptomics data, showing improved accuracy over existing methods.

This study shows that miR-29 is essential for adult cardiomyocyte function, as its deficiency leads to dilated cardiomyopathy and mitochondrial dysfunction in mice and human cells.

This study shows that inhibiting p38 in T cells increases IL-35 production, which enhances thermogenesis and protects against obesity.

This paper shows that MKK6 deficiency leads to cardiac dysfunction through hyperactivation of the MKK3-p38γ/δ-mTOR pathway, causing hypertrophy and fibrosis, and highlights potential cardiotoxicity of p38 inhibitors.