Author

Carolina Q. Sacramento

Instituto Oswaldo CruzORCID 0000-0003-3952-7099Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Jairo Ramos TemerozoiD· 2 shared Natalia Fintelman RodriguesiD· 2 shared Thiago Moreno L. SouzaiD· 2 shared Ahmad Jawad Sabir· 1 shared Aline Dias da PurificaçãoiD· 1 shared Bianca Aparecida MartiniD· 1 shared Brett EatoniD· 1 shared Bruna Fleck GodoiiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Jairo Ramos TemerozoORCID

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3 papers

Recent·Most cited

MicrobiologyAntiviral ResearchPeer-reviewedFeb 17, 2025

Recombinant Pichinde reporter virus as a safe and suitable surrogate for high-throughput antiviral screening against highly pathogenic arenaviruses

Carolina Q. Sacramento, Ryan Bott, Qinfeng Huang…·Lijun Rong

This paper develops a high-throughput screening assay using a non-pathogenic arenavirus to identify antiviral compounds against highly pathogenic arenaviruses.

5 citations

mouseexperimental assay

𝕏 PostBluesky

BiochemistryACS OmegaPeer-reviewedFeb 28, 2024

Unveiling the antiviral capabilities of targeting Human Dihydroorotate Dehydrogenase against SARS-CoV-2

Aline Dias da Purificação, Sabrina Silva Mendonça, Luiza V. Cruz…·Maria Cristina Nonato

This study identifies quinone-based compounds that inhibit HsDHODH and show anti-SARS-CoV-2 activity with low toxicity and nanomolar IC50.

11 citations

humanstatistical model

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NeuroscienceStem Cell ResearchPeer-reviewedJun 20, 2021

Non-permissive SARS-CoV-2 infection in human neurospheres

Carolina da S. G. Pedrosa, Livia Goto‐Silva, Jairo Ramos Temerozo…·Marília Zaluar P. Guimarães

This study shows SARS-CoV-2 infection of human neural cells is non-permissive but causes inflammation and cell damage, suggesting neural damage in COVID-19 is due to systemic inflammation rather than direct viral replication.

33 citations

humanexperimental assay

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