Nicholas Feasey

The paper develops a rules-based classifier to predict ciprofloxacin resistance in Klebsiella pneumoniae from genotype data and demonstrates its global distribution association with quinolone consumption.

This study examines how sub-inhibitory concentrations of ceftriaxone, combined with colistin and kanamycin, affect intracellular transposition in Escherichia coli, identifying thresholds for environmental impact.

This study compares laboratory evolution of piperacillin-tazobactam resistance in Klebsiella grimontii with within-patient resistance evolution, showing that small population bottlenecks reproduce key resistance mechanisms observed in clinical isolates.

The paper uses whole-genome sequencing to study ESBL-Ec transmission networks in rural Malawi, finding high colonization rates and multi-household spread.

This study evaluates screening methods to detect ESBL-producing E. coli and K. pneumoniae in healthcare environmental samples, finding that 18-hour pre-enrichment and specific selective agar improve detection.

The paper introduces TyphiNET, a dashboard for exploring Typhi genomics data to support public health decisions on antimicrobial resistance and vaccine implementation.

The paper investigates the re-emerging chloramphenicol susceptibility in ESBL-producing Enterobacterales by analyzing genotype-phenotype discordance and molecular mechanisms.

The paper uses whole genome sequencing to show high diversity and transmission of ESBL-Ec across human, animal, and environmental compartments in low-income settings, supporting the One Health approach for AMR control.

The paper isolates Salmonella from gecko stool samples in Malawi and shows they carry multiple serovars, suggesting a role in household transmission.

The paper develops a real-time PCR assay to differentiate Salmonella Enteritidis clades for public health surveillance in resource-limited settings.

MagnaExtract is a magnetic bead-based DNA extraction method for detecting antimicrobial resistance genes in river water, showing comparable or better performance than commercial kits and crude methods.

The paper investigates a suspected MDR K. pneumoniae outbreak using whole-genome sequencing to identify strain types and resistance genes.

rPinecone defines sub-lineages in low-variant bacterial populations using phylogenetic trees to improve outbreak and endemic disease analysis.

The paper identifies a non-coding SNP in the pgtE promoter of Salmonella ST313 that increases PgtE expression, contributing to serum resistance and virulence in a chicken model.