Yiqin Xiong

This study establishes a PDX and PDC platform to identify therapeutic vulnerabilities in endometrial cancer, revealing that epigenetic combination therapies show significant antitumor activity.

This study develops a conditional NLRC4 knock-in mouse model that recapitulates the clinical features of autoinflammatory enterocolitis in infants.

This study identifies SETDB1's dual role in endometrial cancer by promoting tumor growth and enabling immune evasion through gene regulation and macrophage suppression.

This study examines FABP4 and FABP5 expression in breast cancer tissues, finding distinct roles in tumor progression and suggesting their potential as prognostic markers and therapeutic targets.

This study shows that FABP4 in tumor-associated macrophages promotes breast cancer metastasis by mediating lipid accumulation and lipolysis in response to unsaturated fatty acids.

This study shows that LRRK2 G2019S promotes colon cancer by enhancing intestinal inflammation and tumor growth in mice.