Ying Zhu

The paper reports an extended structure of the human nuclear pore complex, revealing TREX-2 components as integral parts of the nuclear ring.

The paper maps the spatial and structural proteome architecture of HEK293 cells using subcellular fractionation and cross-linking mass spectrometry, identifying residue-level protein interactions and expanding the human cell interactome.

This paper structurally characterizes CCDC127 as a mitochondrial intermembrane space protein involved in the mitoskeleton framework.

This study identifies two Hippo signaling modules, HPO1 and HPO2, that regulate hepatocyte and cholangiocyte maturation at distinct developmental stages and spatial contexts in mouse livers.

This paper introduces CLASP, a cross-link assisted spatial proteomics method, to map sub-organelle proteomes and membrane protein topology in human mitochondria.

This study identifies Rtc5 and Oxr1 as TLDc domain-containing proteins that regulate V-ATPase assembly and subcellular localization in yeast.

XlinkCyNET is a Cytoscape plugin for visualizing protein interaction networks derived from cross-linking mass spectrometry data.