Felipe Merino

This paper introduces an automated copolymer screening platform for membrane protein solubilization, showing next-generation copolymers outperform classical ones across multiple human targets.

The paper determines the cryo-EM structure of a full-length human β1-adrenergic receptor in complex with Gs, revealing structural insights into ICL3's role in G protein activation.

The paper compares the binding kinetics and structural features of silent and stimulatory flagellin variants with TLR5, identifying structural differences that explain their distinct immune responses.

This paper presents a computational model of GfcD, an outer-membrane β-barrel protein, showing it facilitates lipid-anchored polysaccharide export through a lateral aperture.

This paper determines the structure of the Lifeact-F-actin complex and shows how Lifeact competes with other actin-binding proteins, affecting cell morphology.

This paper presents the first high-resolution cryo-EM structure of ClpXP from Listeria monocytogenes, revealing the binding interface and activation mechanism of the complex.