Yibing Wu

This study shows that random sequences repeated in tandem are more likely to fold into stable structures than fully random sequences, with some structures being novel and experimentally confirmed.

This paper designs drug-binding proteins with low nanomolar affinity and predictable specificity using computational methods, validated by experimental measurements and structural analysis.

The paper uses primate genetic data to predict human variant pathogenicity with a deep learning classifier trained on 4.3 million common missense variants.