Zaoxu Xu

OCellus is a language model that addresses limitations in single-cell, spatial, and perturbation biology by integrating natural-language reasoning across multiple tasks.

This paper introduces a sequencing-based spatial transcriptomics system with sub-cellular resolution and significantly improved capture efficiency compared to existing methods.

The paper reports a near-complete genome assembly of a great bustard using frozen wild samples, revealing ancestral karyotype features and low genetic diversity.

This study creates the first single-cell chromatin accessibility atlas of the lancelet, revealing regulatory elements and developmental trajectories.

This study creates the first single cell atlas of T21 cerebral cortex, identifying dysregulated genes and developing a platform for data exploration.

This study uses single-cell RNA-seq to analyze human infant retina, identifying cell types, communication networks, and developmental changes, providing a resource for retinal research and regenerative medicine.

This study uses single-cell RNA sequencing to analyze the cellular diversity and molecular markers in the retina of a trisomy 21 fetus, revealing communication networks and novel markers.

FabriEVEs is a database that collects, classifies, and annotates endogenous viral elements in non-mammalian species, enabling comparative analysis and host-virus co-evolution studies.