Al Ozonoff

This paper develops an extraction-free qPCR workflow for direct whole-blood testing of viral pathogens, achieving detection limits of 10 copies/uL for DNA and 100 copies/uL for RNA in spiked blood samples.

This paper identifies 23 candidate causal genes for critical COVID-19 by integrating severity-stratified, longitudinal cis-eQTL mapping with GWAS signals from 1,031 patients.

This study identifies eltrombopag olamine and quercetin as CCHFV entry inhibitors using a BSL-2 pseudotype screening platform validated against authentic CCHFV under BSL-4 conditions.

This paper designs an mRNA-LNP vaccine by integrating RNA, lipid, and antigen engineering to achieve 90% protection in a murine model.

Delphy provides a fast, scalable Bayesian phylogenetic analysis tool for outbreak tracking, achieving 1,000x speedups while maintaining state-of-the-art accuracy.

The paper identifies a multi-omics recovery factor predictive of long COVID using data from the IMPACC study, showing it can predict LC risk early after infection.

This study identifies immune subtypes in hospitalized COVID-19 patients linked to clinical outcomes and long COVID risk through longitudinal multi-omics analysis.

This study investigates viral reactivation in COVID-19 patients, finding associations between reactivation of specific virus families and clinical outcomes, including mortality and PASC symptoms.

This study identifies immune programs linked to COVID-19 severity and mortality through longitudinal multi-omics analysis of 1,152 hospitalized patients.