Author

Jongwon Lim

University of Illinois Urbana-ChampaignORCID 0000-0002-0961-117XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:statistical model· 1

Frequent Co-Authors

An Bao VaniD· 2 shared Enrique ValeraiD· 2 shared Katherine KoprowskiiD· 2 shared Matthew WesteriD· 2 shared Rashid BashiriD· 2 shared Al OzonoffiD· 1 shared Bryan HsuiD· 1 shared Colby Wilkason· 1 shared

Activity by Year

2026-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersMolecular Biology

An Bao VanORCID

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3 papers

Recent·Most cited

Molecular BiologybioRxivPreprintNov 12, 2026

Direct Whole-Blood PCR for Molecular Diagnostics

Jongwon Lim, Elyse Stachler, Stella Nielsen…·Pardis Sabeti

This paper develops an extraction-free qPCR workflow for direct whole-blood testing of viral pathogens, achieving detection limits of 10 copies/uL for DNA and 100 copies/uL for RNA in spiked blood samples.

DOI 10.64898/2026.11.10.765582

bulk RNA-seqexperimental assay

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Molecular BiologyProceedings of the National Academy of SciencesPeer-reviewedMay 21, 2026

Amplification-Free Dual-Blocking Autocatalytic CRISPR-Cascade for Atto-Molar DNA Detection with Low Nonspecific Signal

Jongwon Lim, An Bao Van, Matthew Wester…·Rashid Bashir

This paper introduces a dual-blocking CRISPR-Cascade system that reduces background signal and enables sensitive, amplification-free DNA detection.

7 citationstop 1%

DNA methylationexperimental assay

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BioengineeringbioRxivPreprintMar 4, 2026

Kinetic Modeling of Target-Amplification-Free CRISPR-Cas-Based Autocatalysis Reactions

Matthew Wester, Jongwon Lim, An Bao Van…·Rashid Bashir

This paper develops a kinetic model for CRISPR-Cas-based autocatalytic assays to improve understanding and design of target-amplification-free systems.

1 citation

statistical modelbenchmarking

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