Author
University of WashingtonORCID 0000-0003-4255-9550Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Adam J. Broerman, Christoph Pollmann, Yang Zhao…·David A. Baker
The paper designs proteins with controlled dissociation rates by introducing strained excited states, enabling rapid cytokine receptor dissociation.
Sharona E. Gordon, Eric G.B. Evans, Shauna C. Otto…·William N. Zagotta
This paper expands the working distance of tmFRET to 50 Å using new ligands, enabling precise measurement of conformational changes in maltose binding protein under physiological conditions.
William N. Zagotta, Eric G.B. Evans, Pierce Eggan…·Sharona E. Gordon
This paper develops a fluorescence method to measure protein conformational dynamics and energetics using time-resolved tmFRET and validates it with EPR spectroscopy.