Emma Puighermanal

The paper identifies PKR as a critical mediator of mitochondrial neuropathology in a mouse model of Leigh syndrome, showing its role in neuroinflammation and disease progression.

The paper generates and characterizes the first mouse model with a dominant-negative glycine substitution in collagen VI alpha chains, showing key disease features for therapeutic research.

This study investigates the role of dopamine D2 autoreceptors in regulating VTA dopamine neuron responses to aversive stimuli and finds they act as a regulatory brake with sex-biased effects on threat processing.

The paper identifies CCK-expressing vestibular neurons as key drivers of motion-induced malaise and shows their role in inducing conditioned taste aversion through parabrachial nucleus activation.

This study shows that dopamine D2 receptors in the extended amygdala are crucial for switching between passive and active defensive behaviors in response to threats.

This paper shows that d-amphetamine and methylphenidate increase GluA1 phosphorylation at Ser845 in mouse cerebellar Bergmann Glia Cells via norepinephrine signaling.

This study shows that mTOR-RhoA signaling in direct striatal projection neurons affects behavior and striatal physiology in mice, with implications for treating mTOR-related disorders.

This study shows that cerebellar dopamine D2 receptors in Purkinje cells regulate social novelty preference in mice without affecting motor functions.