Andreas Hofmann

This study compares the structural properties of the N-terminal domains of human paraplegin (SPG7) and bacterial FtsH, revealing differences in oligomerization and domain-swapping that may contribute to AAA protease function and disease.

This paper identifies a helminth chitinase with immunomodulatory effects in a murine allergic model, showing structural similarity to mammalian chitinase and inducing cross-reactive antibodies.