TARGETING THE CAPSULE OF KLEBSIELLA PNEUMONIAE WITH A CATIONIC CR3-BINDING PROTEIN ENHANCES PHAGOCYTOSIS AND PROMOTES BACTERIAL CLEARANCE AND SURVIVAL IN A MOUSE SEPSIS MODEL
Nataly P. Podolnikova, Iryna Klymenko, James Alagna…·Tatiana P. Ugarova
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Arizona State UniversityORCID 0000-0003-4449-5140Unclaimed ORCID profile · follow to get notified of new preprints
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Nataly P. Podolnikova, Iryna Klymenko, James Alagna…·Tatiana P. Ugarova
Hoa Nguyen, Nataly P. Podolnikova, Tatiana P. Ugarova, Xu Wang
The paper investigates how the MI-domain of Integrin Mac-1 binds the cytokine pleiotrophin using multiple mechanisms, showing both metal-independent and metal-dependent interactions.
Nataly P. Podolnikova, Valeryi K. Lishko, Robert W. Roberson…·Tatiana P. Ugarova
This study shows that recombinant PF4 enhances phagocytosis of both antibiotic-susceptible and methicillin-resistant S. aureus in vitro and improves survival in a murine peritonitis model.