Cell BiologyJCI InsightPeer-reviewed
Targeting Fibroblast-Endothelial Interactions in LAM Pathogenesis: 3D Spheroid and Spatial Transcriptomic Insights for Therapeutic Innovation
Sinem Koç-Günel, E. C. Liu, Lalit Kumar Gautam…·Amy L. Ryan
The paper uses 3D spheroids and spatial transcriptomics to identify LAMFs and LECs as key contributors to LAM, with bFGF and VEGF-A as potential therapeutic targets.
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