Author

Yuguo Huang

Sichuan UniversityORCID 0000-0003-4523-2289Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Evolutionary Biology· 2 Genetics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Assay:whole-genome sequencing· 4 Organism:human· 3 Research Focus:variant calling· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Guanglin HeiD· 4 shared Mengge WangiD· 4 shared Chao LiuiD· 3 shared Chuan‐Chao WangiD· 3 shared Jiangwei YaniD· 3 shared Jie ZhongiD· 3 shared Junbao YangiD· 3 shared Liping HuiD· 3 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersEvolutionary Biology

Guanglin HeORCID

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4 papers

Recent·Most cited

Evolutionary BiologybioRxivPreprintAug 13, 2025

Helicobacter pylori genome aggregation database reveals complex evolutionary forces shaping its genomic landscape and clinical impact in East Asia

Lintao Luo, Xiaoqiong Tang, Hao Chen…·Guanglin He

The paper introduces HPgnomAD, a global H. pylori genome database revealing evolutionary patterns and clinical implications in East Asia.

DOI 10.1101/2025.08.13.669870

viruswhole-genome sequencing

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Evolutionary BiologyGenomics Proteomics & BioinformaticsPeer-reviewedJun 4, 2025

Paternal genomic resources from the YanHuang cohort suggested a Weakly-Differentiated Multi-source Admixture model for the formation of Hans founding ancestral lineages

Zhiyong Wang, Kaijun Liu, Haibing Yuan…·Kun Zhou

The paper analyzes paternal genomic data from the YanHuang cohort to propose a Weakly-Differentiated Multi-source Admixture model for the formation of Han Chinese ancestral lineages.

35 citationstop 1%

humanwhole-genome sequencing

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GeneticsJournal of genetics and genomics/Journal of Genetics and GenomicsPeer-reviewedOct 11, 2023

Distinguished biological adaptation architecture aggravated population differentiation of Tibeto-Burman-speaking people inferred from 500 whole genome data from 39 populations

Yuntao Sun, Mengge Wang, Qiuxia Sun…·Guanglin He

The paper analyzes 500 whole genomes from 39 Tibeto-Burman populations to uncover genetic differentiation and adaptive features linked to geography and environment.

40 citationstop 2%

humanwhole-genome sequencing

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GeneticsbioRxivPreprintAug 28, 2023

Ancient farmer and steppe pastoralist-related founding lineages contributed to the complex landscape of episodes in the diversification of Chinese paternal lineages

Mengge Wang, Yuguo Huang, Kaijun Liu…·Guanglin He

The paper uses ancient DNA and genomic data to trace the genetic contributions of ancient farmer and steppe pastoralist lineages to the paternal genetic diversity of modern Chinese populations.

5 citations

humanDNA methylation

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