Guanglin He

This study uses spatial transcriptomics and snRNA-seq to identify 25 forebrain regions and characterize dynamic changes in the human fetal cortex and striatum during late first and early second trimesters.

This study uses whole-genome sequencing of Central Asians to reveal genetic diversity, admixture events, and adaptive processes shaping their demographic history and medical relevance.

The paper presents genomic data from 1,031 individuals in the Tibetan-Yi Corridor, identifying genetic variants, adaptation signatures, and archaic introgression patterns.

The paper introduces HPgnomAD, a global H. pylori genome database revealing evolutionary patterns and clinical implications in East Asia.

The paper analyzes paternal genomic data from the YanHuang cohort to propose a Weakly-Differentiated Multi-source Admixture model for the formation of Han Chinese ancestral lineages.

The paper identifies a novel DMD mutation causing cryptorchidism through whole-genome sequencing and CRISPR-Cas9 mouse modeling.

The paper analyzes 500 whole genomes from 39 Tibeto-Burman populations to uncover genetic differentiation and adaptive features linked to geography and environment.

The paper uses ancient DNA and genomic data to trace the genetic contributions of ancient farmer and steppe pastoralist lineages to the paternal genetic diversity of modern Chinese populations.

This study analyzes 796 Tai-Kadai genomes to uncover genetic adaptations and evolutionary history, revealing Malaria resistance and population structure in TK-speaking groups.

The paper uses whole-genome sequencing of 126 individuals from six ethnolinguistic groups in Northwest China to study genetic admixture and biological adaptations along the Silk Road.

This study analyzes 440 Hmong-Mien genomes to reveal genetic differentiation, admixture, and migration patterns, supporting isolation and long-distance migration.

The paper develops a high-resolution Y-SNP panel to infer paternal lineages and admixture history in Chinese populations, revealing complex genetic diversity and migration patterns.

Reanalysis of Robbeets et al.'s linguistic, genetic and archaeological datasets finds that none supports a Transeurasian language family or its spread with West Liao River Neolithic millet farmers.

The paper identifies 21 novel microhaplotype markers for ancestry inference in ten Chinese subpopulations, showing higher accuracy than SNP-based panels.

This study clarifies the genetic origin and admixture history of the Tanka people using population genomic analysis of modern and ancient Eurasian samples.

The paper uses genome-wide array genotyping to infer northern gene flow into southeastern East Asians by analyzing present-day and ancient populations.

This study analyzes genome-wide SNPs from Hmong-Mien speakers to reveal genetic substructure, a new ancestral lineage, and adaptive signatures linked to nervous system functions.

This paper analyzes genomic data from Sherpa people to explore their genetic origin, evolutionary history, and forensic characteristics using InDels and SNPs.

The paper analyzes genome-wide SNP data from Sanya Hui people to infer their genetic origins and admixture history, revealing tripartite origins from Central Vietnam, East Asia, and Central/South Asia.

This paper uses modern and ancient genome-wide data to infer multiple waves of admixture and the peopling of the Tibet Plateau, identifying genetic connections and population stratifications among Tibetans and East Asians.

This study analyzes genome-wide SNP data from 510 individuals across 38 Mongolic, Tungusic, and Sinitic populations to explore genetic structure, admixture history, and demographic patterns in North-East Asia.

The paper reconstructs the demographic history of Tai-Kadai and Sinitic people in South China using genome-wide data and reference datasets, revealing genetic contributions from millet and rice farmers.

This study analyzes genomic data to determine the origin and genetic structure of Chinese Hui people, finding strong East Asian affinity and supporting a cultural diffusion model over demic diffusion.

The paper evaluates an ancestry panel using 165 SNPs in three southern Chinese populations, showing improved forensic performance over STR-based systems but limitations in intercontinental ancestry inference.

Genome-wide SNPs from 211 Southern Chinese, analysed with over 1,200 ancient and modern genomes, split the Yangtze River Farmer lineage into four language-linked sub-ancestries and date later migrations.

This paper uses ancient and present-day genomic data to reconstruct the population history of East Asia, identifying key migrations and language dispersals.