Frédéric Bringaud

This study identifies glycerol as a trigger for Trypanosoma brucei differentiation into transmissible forms under tissue-like conditions, challenging the traditional bloodstream model of transmission.

This study identifies and characterizes TbPat, a triacylglycerol lipase in Trypanosoma brucei, showing its role in lipid mobilization and differentiation.

This paper shows that ATP-dependent phosphofructokinase (PFK) in Trypanosoma brucei functions gluconeogenically in vivo, challenging its traditional role in glycolysis.

This study investigates the transport and metabolic roles of serine, threonine, and glycine in Trypanosoma cruzi, showing their importance in energy metabolism and stress response.

This paper demonstrates a marker-free gene editing method using SpCas9 ribonucleoprotein complexes in trypanosomatids, enabling efficient genetic modifications in various life stages of T. brucei, T. congolense, and Leishmania promastigotes.