Jinhua Wang

The paper identifies age-associated differential transcript usage in mouse tissues, showing regulatory isoform switching with tissue-specific structural consequences.

The paper identifies age-dependent senescent endothelial cells in adipose tissue using snRNA-Seq and finds ion channel genes as predictive biomarkers.

This study shows that cellular senescence disrupts liver zonation and hepatocyte function with age by altering gene expression and cell signaling.

The paper quantifies transposable element (TE) expression at both subfamily and locus levels during human endoderm differentiation, finding locus-level analysis reveals distinct transcriptional dynamics at cell division boundaries.