Author

Maximilian Klaus Nocke

Ruhr University BochumORCID 0000-0003-4632-525XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Approach:statistical model· 1

Frequent Co-Authors

Daniel TödtiD· 2 shared Eike SteinmanniD· 2 shared Volker KinastiD· 2 shared André GömeriD· 1 shared George Liam SsebyatikaiD· 1 shared Jil Alexandra HaaseiD· 1 shared Juliana Janzen· 1 shared Mara KlöhniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Daniel TödtORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintSep 17, 2026

Impact of hepatitis E virus host- and virus-derived insertions on the antiviral response in primary human hepatocytes

Sarah Schlienkamp, Maximilian Klaus Nocke, Rainer G. Ulrich…·Daniel Tödt

This study examines how different HEV HVR insertion variants affect host transcriptomic responses in PHHs, finding that HVR duplication variants elicit weaker host responses and reduced ISG induction.

DOI 10.64898/2026.09.15.750637

humanbulk RNA-seq

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Cell BiologyHepatologyPeer-reviewedMay 10, 2024

Targeting cellular cathepsins inhibits hepatitis E virus infection

Mara Klöhn, Thomas L. Burkard, Juliana Janzen…·Eike Steinmann

This study identifies lysosomal cathepsins, particularly CTSL, as critical for HEV entry and demonstrates the antiviral efficacy of the pan-cathepsin inhibitor K11777.

34 citationstop 3%

humanexperimental assay

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