Anubama Rajan

This study uses human nasal epithelial organoids to investigate how different bacteria colonize nasal tissue and induce cytokine responses, finding differential effects on chemokines and inflammasome signaling.

The paper examines longitudinal transcriptional responses to SARS-CoV-2 infection in adults with varying viral loads, identifying gene expression patterns and host responses over time.

This study compares RSV infection responses in pediatric and adult nose organoids, finding pediatric organoids show greater susceptibility, cytokine response, and cellular damage.

The paper investigates E. coli strains from cancer patients with diarrhea, finding novel adherence patterns and high antibiotic resistance gene carriage.

This study identifies major sources of transcriptomic variation in human intestinal organoids, showing that culture methods like substrate and format have large effects compared to experimental manipulations.

This study develops an oligonucleotide capture sequencing method to generate SARS-CoV-2 genomic and transcriptome sequences from clinical samples, revealing differential transcriptional activity and ORF10 expression.