Jack W Shepherd

This paper develops a method to measure molecular transport in biofilm mimics using quantum dots and high-speed microscopy, showing reduced diffusion coefficients in hydrogel models.

Live E. coli gyrase clusters hold excess GyrB (B:A 2.5:1), show hexanediol-sensitive liquid-like turnover, and docking suggests GyrB bridges heterotetramers.

This study shows that varying the number of binding motifs in a disordered protein affects pyrenoid assembly and algal fitness.

The paper introduces COMBI-Tweez, a tool combining optical and magnetic tweezers with fluorescence microscopy to study the structural dynamics of single chiral biopolymers like DNA under mechanical forces.