Manuela Leal da Silva

This study uses high-resolution computational modeling to uncover new molecular interactions between T. cruzi gp82 and LAMP2, revealing cooperative motions critical for host-cell invasion.

This study shows that the E. coli TolC protein is immunogenic, inducing antibody production that enhances macrophage uptake and survival against E. coli infection.

The paper predicts functional domains of hypothetical proteins in Trypanosomatids to identify potential drug targets, finding three promising domains with conservation and multi-species impact.