Author

Long Sun

The University of Texas Medical Branch at GalvestonORCID 0000-0003-4889-4624Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:virus· 1

Frequent Co-Authors

Xuping XieiD· 2 shared Benjamin W. NeumaniD· 1 shared Colin K. SkepperiD· 1 shared Daniela Barriga· 1 shared Demonta D. ColemaniD· 1 shared Jason YeungiD· 1 shared Jing Xiao· 1 shared Jing ZouiD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersMicrobiology

Xuping XieORCID

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2 papers

Recent·Most cited

MicrobiologyProceedings of the National Academy of SciencesPeer-reviewedMar 28, 2025

Mechanistic Insights into Dengue Virus Inhibition by a Clinical Trial Compound NITD-688

Yan Wang, Long Sun, Luciana de Souza Fernandes…·Xuping Xie

This study identifies how NITD-688 inhibits dengue virus by binding NS4B and disrupting its interaction with NS3, reducing viral replication.

21 citationstop 1%

virusexperimental assay

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BiochemistryJournal of Medicinal ChemistryPeer-reviewedApr 12, 2024

Discovery of First-in-Class PROTAC Degraders of SARS-CoV-2 Main Protease

Yugendar R. Alugubelli, Jing Xiao, Kaustav Khatua…·Shiqing Xu

This paper develops first-in-class PROTAC degraders of SARS-CoV-2 main protease, showing they reduce MPro levels and exhibit anti-SARS-CoV-2 activity.

89 citationstop 1%

experimental assaydrug response / drug discovery

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