Anne‐Claude Gavin

The paper identifies lipid cargoes for half of analyzed human LTPs, revealing selectivity for lipid head groups and acyl chains and new lipid-organelle relationships.

The paper maps lipid species across human cell compartments using PAP-SL and identifies general rules of lipid organization and metabolic plasticity.

The paper proposes a membrane-assisted mechanism for ceramide release from the CERT START domain using molecular simulations and validates it with experimental lipidomics data.

This study investigates how human STARD4 binds to membranes and transfers cholesterol, showing lipid composition and cargo influence its activity.

This study develops genetically encoded fluorescent probes based on KSR1's ceramide-binding domain to track ceramide dynamics during phagocytosis and identifies distinct behaviors of different probe variants.

This study shows APOE alleles E2, E3, and E4 differentially affect astrocyte metabolism, cholesterol handling, and inflammation in isogenic iPSC-derived cells, with E4 showing disease-relevant dysregulation.

This study uses multiomics analysis of BMSCs to show age-related changes in enhancer activity and gene regulation contribute to immune traits and tissue-specific disorders.

The paper introduces SF-Matching, a machine learning method for metabolite identification from MS/MS spectra using structural features, achieving high accuracy when combined with CSI:FingerID.