Transcriptional Dysregulation in the Hippocampus of a murine model for Parkinson's Disease Cognition Impairment is Driven by Sex, Age, and Alpha-synuclein overexpression
Alessia Sciortino, Thomas Hentrich, Sergio Helgueta…·Manuel Buttini
Author
University of LuxembourgORCID 0000-0003-4983-9934Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Alessia Sciortino, Thomas Hentrich, Sergio Helgueta…·Manuel Buttini
Kristopher J. Schmit, Alessia Sciortino, Velma T. E. Aho…·Paul Wilmes
This study shows that dietary fibre deprivation and bacterial curli exposure worsen PD-like symptoms in mice overexpressing human alpha-synuclein.
Diana M. Hendrickx, Pierre Garcia, Amer Ashrafi…·Enrico Glaab
This study uses a synuclein-transgenic mouse model to identify molecular changes in early Parkinson's disease before neurodegeneration occurs.
Pierre Garcia, Wiebke M. Wemheuer, Oihane Uriarte Huarte…·Manuel Buttini
The paper investigates the role of alpha-synuclein spreading and inclusions in Parkinson disease using a mouse model, finding that neurodegeneration and microgliosis occur independently of inclusions.