Author

Sercan Aksoy

Hacettepe UniversityORCID 0000-0003-4984-1049Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Organism:human· 1 Organism:mouse· 1 Assay:multiome· 1 Assay:proteomics· 1

Frequent Co-Authors

Ayşegül ÜneriD· 2 shared Meral ÜneriD· 2 shared Metin ÇetįniD· 2 shared Mustafa Emre GedikiD· 2 shared Özge SaatciiD· 2 shared Özgür ŞahiniD· 2 shared Aynur IşıkiD· 1 shared Aytekin AkyoliD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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2 shared papersCancer Biology

Ayşegül ÜnerORCID

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2 papers

Recent·Most cited

Cancer BiologyCell Death and DiseasePeer-reviewedJun 15, 2024

Targeting LINC00152 activates cAMP/Ca2+/ferroptosis axis and overcomes tamoxifen resistance in ER+ breast cancer

Özge Saatci, Rashedul Alam, Kim‐Tuyen Huynh‐Dam…·Özgür Şahin

This study identifies LINC00152 as a driver of tamoxifen resistance in ER+ breast cancer by inhibiting ferroptosis, and shows that targeting LINC00152 restores sensitivity to tamoxifen.

42 citationstop 3%

humanbulk RNA-seq

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Cancer BiologyCancer ResearchPeer-reviewedFeb 6, 2024

Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer

Mustafa Emre Gedik, Özge Saatci, Nathaniel P. Oberholtzer…·Özgür Şahin

This study shows that T-DM1 induces immunogenic cell death (ICD) in HER2-positive breast cancer, which is lost in resistance, and that targeting TACC3 restores ICD and enhances T-DM1 response.

46 citationstop 2%

mouseproteomics

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