Murilo Sena Amaral

This paper reviews pre-clinical Schistosoma mansoni vaccine studies, finding that only two antigens achieved over 90% efficacy, but most vaccines fall short of required thresholds due to variable formulations and study designs.

The paper identifies evolutionary shifts in lncRNA expression in the developing human cerebral cortex, showing increased de novo expression in excitatory neurons and associations with autism spectrum disorder.

This study shows that inhibiting SmLSD1 with MC3935 causes transcriptional changes and structural damage in Schistosoma mansoni, leading to parasite death.