Highly accurate prophage island detection with PIDE
Hongyan Gao, Bowen Li, Zihan Guo…·Guanxiang Liang
PIDE detects prophages in bacterial genomes and metagenomes with high accuracy using a protein language model and gene density clustering.
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Center for Life SciencesORCID 0009-0000-1548-7825Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
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Hongyan Gao, Bowen Li, Zihan Guo…·Guanxiang Liang
PIDE detects prophages in bacterial genomes and metagenomes with high accuracy using a protein language model and gene density clustering.
Lei Zheng, Bowen Li, Siqi Xu…·Guanxiang Liang
FEDKEA improves enzyme function prediction by combining a pretrained protein language model with distance-weighted k-nearest neighbor, outperforming existing tools.
Chunling Duan, Moorim Kang, Kunshan Liu…·Long‐Cheng Li
This study introduces RD-12500, an siRNA conjugate that effectively reduces SOD1 levels and delays disease progression in late-stage SOD1G93A ALS mice.