Highly accurate prophage island detection with PIDE
Hongyan Gao, Bowen Li, Zihan Guo…·Guanxiang Liang
PIDE detects prophages in bacterial genomes and metagenomes with high accuracy using a protein language model and gene density clustering.
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Center for Life SciencesORCID 0000-0002-7367-2516Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
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Hongyan Gao, Bowen Li, Zihan Guo…·Guanxiang Liang
PIDE detects prophages in bacterial genomes and metagenomes with high accuracy using a protein language model and gene density clustering.
Lei Zheng, Bowen Li, Siqi Xu…·Guanxiang Liang
FEDKEA improves enzyme function prediction by combining a pretrained protein language model with distance-weighted k-nearest neighbor, outperforming existing tools.
Bowen Li, Xianyue Jiao, Guanxiang Liang
iVirP is a pipeline for annotating viral contigs from metagenome or VLP sequencing data, improving accuracy and efficiency in virome analysis.
ESM-PVP uses a pretrained protein language model and an MLP to identify and classify phage virion proteins, outperforming previous methods on a new benchmark dataset.
Yongjuan Guan, Hongyan Gao, Nicolae Adrian Leu…·P. Jeremy Wang
This study shows MOV10 restricts LINE1 retrotransposition in mice in a dosage-dependent manner, affecting reproductive fitness and transcriptome regulation.