Devanarayanan Siva Sankar

A parallelized BindCraft pipeline generated 306,146 in silico binder candidates against 8,296 human proteins, each with sequence, predicted complex and confidence metrics, freely accessible online.

This study identifies VRK-1 as a regulator of chromatin-nuclear lamina interactions in C. elegans, showing its role in stress-induced chromatin reorganization and survival.

The paper identifies Acl1 and Bcl1 as dedicated chaperones for Rpl1 by using proximity labeling and structural analysis in yeast.

This study shows that autophagy-dependent loss of ribosomal proteins during starvation in C. elegans balances survival and recovery speed by affecting growth resumption.

This study identifies BAG2 as an effector of the ULK1 complex that modulates AMBRA1 localization to regulate autophagy initiation under different nutritional conditions.

The paper measures collagen content in mice tissues and whole bodies, finding collagen constitutes 12% in females and 17% in males of total protein.