Author

Freddy Van Goethem

Vrije Universiteit Brussel, Department of In Vitro Toxicology and Dermato-Cosmetology;ORCID 0009-0000-5672-0048Unclaimed ORCID profile · follow to get notified of new preprints

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Anouck I. ThienpontiD· 1 shared Birgit MertensiD· 1 shared Emmanuel DemuynckiD· 1 shared Joost B. BeltmaniD· 1 shared Levi M.T. WinkelmaniD· 1 shared Maciej StepnikiD· 1 shared Marc AudebertiD· 1 shared Sanah MajidiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperPharmacology & Toxicology

Anouck I. ThienpontORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintNov 13, 2026

Advancing AOPs for genotoxicity through quantifying KERs linking DNA alkylation to increase in mutations and chromosome aberrations

Levi M.T. Winkelman, Emmanuel Demuynck, Steven M. Bryce…·Joost B. Beltman

This study develops a quantitative adverse outcome pathway for genotoxicity by modeling relationships between DNA alkylation and mutations/chromosome aberrations using existing data.

DOI 10.64898/2026.11.11.765894

humanbulk RNA-seq

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