Junying Zheng

This study shows that senescent bone marrow adipocytes secrete SAP/PTX2, which promotes skeletal amyloidosis and bone loss in aging mice.

This study identifies senescent osteoclasts in spinal models as contributors to pain through nerve growth and vessel formation, showing their removal reduces hypersensitivity.

The paper identifies a novel subtype of reactive astrocytes, HIPAs, critical for HIV-associated pain pathogenesis in mice and humans.

This study uses scRNA-seq to compare microglia in adult mouse brains and spinal cords, identifying subtype differences and plasticity in response to HIV-1 gp120.