Author
Montreal Neurological Institute and HospitalORCID 0009-0001-7756-1661Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Esther del Cid‐Pellitero, Thomas Goiran, Zaid A.M. Al‐Azzawi…·Edward A. Fon
This study shows that N-terminal acetylation of α-synuclein reduces aggregation, uptake, seeding, and toxicity in Parkinson's disease models.
Sitki Cem Parlar, Eric Yu, Sajanth Kanagasingam…·Ziv Gan‐Or
The paper integrates machine learning and rare variant burden analysis to identify novel candidate genes for Parkinson's disease.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio…·Adriano Aguzzi
The paper uses CRISPR screens to identify OXR1 and EMC4 as modifiers of α-synuclein aggregation in Parkinson's disease and related synucleinopathies.
Jace Jones-Tabah, Kathy He, Nathan C. Karpilovsky…·Edward A. Fon
This study investigates the role of cathepsin B in Parkinson's disease by analyzing genetic variants and manipulating catB function in cell models to assess its impact on lysosomal activity and alpha-synuclein clearance.
Mohamed A. Eldeeb, Andrew N. Bayne, Armaan Fallahi…·Edward A. Fon
This study shows PINK1 forms a supercomplex with TOM and TIM23 during mitochondrial stress and is required for tethering TOM to TIM23, which is essential for mitophagy.