Author

Yih-An Chen

University of California, San FranciscoORCID 0009-0001-7767-8464Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:scRNA-seq· 2 Research Focus:benchmarking· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Franklin W. HuangiD· 3 shared Hanbing SongiD· 3 shared Julia H. PhamiD· 3 shared Hannah N. W. WeinsteiniD· 2 shared Jon AkutagawaiD· 2 shared Keliana S F HuiiD· 2 shared Andrew O. GiacomelliiD· 1 shared Arda Demirci· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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3 shared papersGenomics

Franklin W. HuangORCID

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3 papers

Recent·Most cited

GenomicsbioRxivPreprintMar 27, 2026

A single-cell and spatial atlas of prostate cancer reveals the combinatorial nature of gene modules underlying lineage plasticity and metastasis

Hanbing Song, Junxiang Xu, Keila Velázquez-Arcelay…·Franklin W. Huang

The paper constructs a single-cell and spatial atlas of prostate cancer to reveal gene modules driving lineage plasticity and metastasis, identifying new biological insights and a transformer-based model for cell-state classification.

3 citations

humanscRNA-seq

𝕏 PostBluesky

Cancer BiologyCell ReportsPeer-reviewedAug 1, 2024

RPL22 is a tumor suppressor in MSI-high cancers and a key splicing regulator of MDM4

Hannah N. W. Weinstein, Kevin Hu, Lisa Fish…·Franklin W. Huang

This study identifies RPL22 as a tumor suppressor in MSI-H cancers that regulates MDM4 splicing and reveals its role in oncogenic pathways.

30 citationstop 3%

humanexperimental assay

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GenomicsbioRxivPreprintNov 6, 2023

Single cell transcriptional profiling of benign prostatic hyperplasia reveals a progenitor-like luminal epithelial cell state within an inflammatory microenvironment

Rei Unno, Jon Akutagawa, Hanbing Song…·Thomas Chi

This study uses single-cell RNA-seq to identify a luminal progenitor cell state in BPH linked to inflammation and MIF interactions.

2 citations

humanscRNA-seq

𝕏 PostBluesky