Gregor Rot

MicrobeAtlas unifies over two million microbiome samples to enable cross-technology insights into microbial ecosystems and their global patterns.

This study identifies U1 snRNP-associated proteins in Arabidopsis and shows their role in regulating mRNA 3'-end processing through premature cleavage and alternative polyadenylation site selection.

The paper benchmarks eight tools for identifying and quantifying alternative polyadenylation sites from RNA-seq data using real, synthetic, and 3'-end sequencing data.

splicekit provides tools for splicing analysis from short-read RNA-seq data, including alignment, alternative splicing detection, motif discovery, and visualization.

This study characterizes polyadenylation patterns in human articular chondrocytes from healthy and osteoarthritic samples, finding limited polyA site changes in osteoarthritis compared to cancer.