Boris Maček

The paper investigates how gut commensal strains modulate the growth and virulence of Clostridium perfringens through substrate competition and protein level changes.

The paper profiles the proteome of plant Cajal bodies, revealing a distinct kingdom-specific composition compared to animal CBs.

This study identifies Vlf1 as a vacuolar lipophagy regulator in S. cerevisiae, showing its localization to the vacuole and interaction with Atg15, with effects on autophagy levels.

This paper revises the genome annotation of Synechocystis using ribosome profiling and proteogenomics, identifying new genes and correcting existing annotations.

The paper uses proximity labeling to identify proteins interacting with mitochondrial import complexes, revealing EXD2 as a TOM/SAM-associated factor at the mitochondrial outer membrane.

This study shows that KNOLLE protein degradation in plant cytokinesis depends on ubiquitination, which is context-dependent and linked to membrane fusion events.

The paper identifies ERAPS as a system controlling proteasome activator fate during proteotoxic stress, revealing a trade-off between proteasome function and energy metabolism.

This study shows pathogenic bacteria inhibit host translation by targeting processing bodies and reveals a link between ER stress, autophagy, and P-body dynamics.

This study compares mitosis in 3D tumor spheroids and 2D monolayers, finding prometaphase delays and proteomic changes in spheroids.

The paper uses proximity labeling to compare interaction partners of TOMM20 and TOMM70, finding RBPs preferentially associate with TOMM20 and their association increases under translation stress.

The paper shows that Zuo1, a ribosome-associated complex chaperone, mitigates growth defects and translation reduction in yeast with mitochondrial import defects under heat stress.

This study shows that PINK1 regulates cholesterol homeostasis in human dopaminergic neurons by phosphorylating SCAP, and restoring cholesterol levels rescues defects in neurotransmitter uptake.

The paper investigates the role of c-di-AMP and SbtB in cyanobacterial diurnal metabolism, finding that their disruption leads to metabolic dysregulation and diurnal lethality.

This study identifies and characterizes the negamycin biosynthetic gene cluster in Kitasatospora purpeofusca, enabling scalable production through heterologous expression.

This study shows that RUBISCO activity in Synechocystis is regulated by RuBP availability, with CP12 inactivating the CBB cycle during darkness and affecting RuBP levels.

This study shows that parkin-dependent ubiquitination of TAX1BP1's CC3 domain is not essential for mitophagy but reroutes degradation to a less efficient endolysosomal pathway when CC3 is absent.

This study shows that impaired mitochondrial fusion in yeast leads to mtDNA loss due to unequal distribution and reduced synthesis.

This study identifies oxygen's role in enabling renewable n-caprylate production from ethanol and acetate via intermediate metabolite synthesis in bioreactors.

This study investigates the secretion mechanism of transmembrane effector proteins by Legionella T4bSS, revealing a two-step process involving an inner membrane intermediate.

This study identifies U1 snRNP-associated proteins in Arabidopsis and shows their role in regulating mRNA 3'-end processing through premature cleavage and alternative polyadenylation site selection.

This study identifies Vangl1 as a key mediator of flow-dependent cell dynamics in vascular remodeling through planar cell polarity signaling.

This study develops nanobodies to monitor Drp1, a mitochondrial fission factor, using proteomics, microscopy, and live-cell imaging techniques to study its dynamics in disease models.

The paper identifies the epigenetic toolkit of Pristionchus pacificus, revealing the loss of the PRC2 complex and the presence of H3K27me3 through an unknown methyltransferase.

The paper shows that histone 4 lysine 5/12 acetylation regulates developmental plasticity and epigenetic memory in nematodes by controlling switch gene expression during a critical environmental sensitivity window.

This study identifies PINK1's role in regulating mitochondrial function, lipid metabolism, and dopamine homeostasis in dopaminergic neurons, showing that cholesterol depletion can reverse PINK1-related phenotypes.

This study identifies LUC7 as a U1 snRNP accessory protein in Arabidopsis that regulates alternative splicing and is essential for plant development and stress response.