Swetha Maganti

This study shows that disabling PSGL-1 enhances anti-tumor immunity in pancreatic cancer by improving CD8+ T cell function and response to PD-1 blockade.

This study shows that aging stromal cells in pancreatic cancer promote immune exclusion and metastasis, and that rejuvenating these cells can reverse these effects.

This study identifies aPKC enzymes as regulators of macropinocytosis in PDAC cells under glutamine stress, showing their role in cell survival and tumor growth.

This study shows that macropinocytosis regulates CAF subtype identity under metabolic stress in PDAC, impacting tumor stroma and therapeutic response.